Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.57 |
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166468 | 1.00 | PTPN1 (0.57) | PTPN1GSK3BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29758522 | 1.00 | PTPN1 (0.57) | PTPN1GSK3BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9409754 | 0.85 | PTPN1 (0.65) | PTPN1GSK3BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28053559 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL15979732 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL30089542 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL3703924 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL29322296 | 0.81 | PTPN1 (0.52) | PTPN1GSK3BALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8744733 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL12430466 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764017-A4 | METHODS AND COMPOSITIONS FOR DISRUPTING THE EPITHELIAL BARRIER FUNCTION | CELLEGY PHARMA INC (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0764017-A1 | METHODS AND COMPOSITIONS FOR DISRUPTING THE EPITHELIAL BARRIER FUNCTION | CELLEGY PHARMACEUTICALS, INC. (US) | 1997-03-26 | — | — | EP | disclosed |
| WO-1994021230-A1 | METHOD AND COMPOSITIONS FOR DISRUPTING THE EPITHELIAL BARRIER FUNCTION | CELLEGY PHARMACEUTICALS, INC. (US) | 1994-09-29 | — | — | WO | disclosed |