Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961945 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL845125 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL28613135 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL23639428 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL21786269 | 0.73 | ALDH1A1 (0.63) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL25827431 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL23674679 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL15832960 | 0.72 | ALDH1A1 (0.57) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL19838578 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4EGLAGAALMNA | |
| SCHEMBL29792765 | 0.70 | ALDH1A1 (0.54) | ALDH1A1KDM4EGLAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031547-B1 | PLASMA KALLIKREIN INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-17 | — | — | EP | disclosed |