SCHEMBL29323063

SCHEMBL29323063

C#C[C@]1(CO)O[C@@H](c2cnc3c(N)ncnn23)[C@@H](O)C1O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 1/20 0.33
▸ POLRMT O00411 1/20 0.33
▸ ADK P55263 1/20 0.30
▸ DOT1L Q8TEK3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23054690 1.00 STING1 (0.33) STING1POLRMTADKDOT1L
SCHEMBL15259036 0.89 STING1 (0.31) STING1
SCHEMBL29323452 0.85 — —
SCHEMBL29323092 0.84 — —
SCHEMBL23054688 0.84 — —
SCHEMBL29323062 0.83 POLRMT (0.46) STING1POLRMTDOT1L
SCHEMBL23054687 0.83 POLRMT (0.46) STING1POLRMTDOT1L
SCHEMBL29323823 0.83 POLRMT (0.46) STING1POLRMTDOT1L
SCHEMBL29323473 0.82 — —
SCHEMBL17106779 0.82 SLC28A1 (0.30) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY 2024-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES MTAP, PNP, SARS1 STING1 58/4885POLRMT 108/4885ADK 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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