SCHEMBL29323101

SCHEMBL29323101

CC(C)(C)OC(=O)N1CCC(OCC#Cc2ccc3occ(C4CCC(=O)NC4=O)c3c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 12/20 0.44
CRBN Q96SW2 12/20 0.44
ALDH2 P05091 1/20 0.39
CETP P11597 1/20 0.38
GPR119 Q8TDV5 3/20 0.36
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
ALK Q9UM73 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29322999 0.94 DDB1 (0.44) DDB1CRBNALDH2CETPGPR119
SCHEMBL29322908 0.84 DDB1 (0.47) DDB1CRBNGPR119
SCHEMBL29323432 0.84 DDB1 (0.45) DDB1CRBNALDH2CETPGPR119
SCHEMBL29323105 0.82 CRBN (0.35) DDB1CRBNALDH2
SCHEMBL31425858 0.82 CRBN (0.49) DDB1CRBNALDH2
SCHEMBL31425837 0.82 CRBN (0.49) DDB1CRBNALDH2
SCHEMBL24950364 0.80 DDB1 (0.54) DDB1CRBNGPR119
SCHEMBL29322939 0.80 ALDH2 (0.36) DDB1CRBNALDH2
SCHEMBL31425995 0.80 CRBN (0.41) DDB1CRBNALDH2
SCHEMBL21997580 0.77 DDB1 (0.47) DDB1CRBNALDH2CETPGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed