SCHEMBL29322939

SCHEMBL29322939

CN1CCC(OCC#Cc2ccc3c(C4CCC(=O)NC4=O)coc3c2)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH2 P05091 3/20 0.36
CRBN Q96SW2 15/20 0.36
DDB1 Q16531 14/20 0.36
DRD2 P14416 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323000 0.88 ALDH2 (0.36) ALDH2CRBNDDB1
SCHEMBL29322999 0.86 DDB1 (0.44) ALDH2CRBNDDB1
SCHEMBL29331542 0.82 CRBN (0.37) CRBNDDB1
SCHEMBL29322917 0.82 CRBN (0.39) CRBNDDB1DRD2HTR2AHTR2C
SCHEMBL29323105 0.81 CRBN (0.35) ALDH2CRBNDDB1
SCHEMBL29323101 0.80 DDB1 (0.44) ALDH2CRBNDDB1
SCHEMBL24938769 0.76 IDO1 (0.47) CRBNDDB1
SCHEMBL31426233 0.73 CRBN (0.40) CRBNDDB1
SCHEMBL31425905 0.73 CRBN (0.39) CRBNDDB1
SCHEMBL24938746 0.72 CRBN (0.53) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed