SCHEMBL29323386

SCHEMBL29323386

Nc1nc2c(ncn2[C@@H]2C[C@H](CO)C(O)[C@@H]2O)c(=O)[nH]1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHCY P23526 6/20 0.65
ADORA2B P29275 1/20 0.60
ADORA3 P0DMS8 1/20 0.57
PNP P00491 3/20 0.53
HPRT1 P00492 3/20 0.52
TK1 P04183 1/20 0.47
STING1 Q86WV6 2/20 0.47
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.46
EDNRA P25101 1/20 0.46
HTR2A P28223 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
HBB P68871 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9877452 1.00 AHCY (0.65) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL9078539 1.00 AHCY (0.65) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL10767171 1.00 AHCY (0.65) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL29325364 1.00 AHCY (0.65) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL1713028 1.00 AHCY (0.65) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL10767166 1.00 AHCY (0.65) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL9367067 0.97 AHCY (0.60) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL10516308 0.97 AHCY (0.60) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL10516867 0.97 AHCY (0.60) AHCYADORA2BADORA3PNPHPRT1
SCHEMBL9020125 0.97 AHCY (0.60) AHCYADORA2BADORA3PNPHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES MTAP, PNP, SARS1 AHCY 804/4885ADORA2B 322/4885ADORA3 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.