Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 5/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 3/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367067 | 1.00 | AHCY (0.60) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL10516867 | 1.00 | AHCY (0.60) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL10516308 | 1.00 | AHCY (0.60) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL29323386 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL10767171 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL9877452 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL1713028 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL10767166 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL29325364 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 | |
| SCHEMBL9078539 | 0.97 | AHCY (0.65) | AHCYADORA3ADORA2BPNPHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322854-B1 | Purinyl cyclobutanes | SQUIBB & SONS INC (US) | 1994-07-13 | — | — | EP | claimed |
| US-4918075-A | Purinyl and pyrimidinyl cyclobutanes and their use as antiviral agents | E. R. SQUIBB & SONS, INC. (US) | 1990-04-17 | — | — | US | claimed |
| EP-0322854-A1 | Purinyl cyclobutanes | E.R. Squibb & Sons, Inc. (US) | 1989-07-05 | — | — | EP | claimed |
| JP-2000780-A | — | — | None | — | — | JP | disclosed |
| EP-0458312-B1 | Novel cyclobutane derivatives | NIPPON KAYAKU KK (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0322854-B1 | Purinyl cyclobutanes | SQUIBB & SONS INC (US) | 1994-07-13 | — | — | EP | disclosed |
| US-5324730-A | Viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-06-28 | — | — | US | disclosed |
| US-5246931-A | Triazine-substituted cyclobutane derivatives; viricides; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-09-21 | — | — | US | disclosed |
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0458312-A1 | Novel cyclobutane derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |
| US-4918075-A | Purinyl and pyrimidinyl cyclobutanes and their use as antiviral agents | E. R. SQUIBB & SONS, INC. (US) | 1990-04-17 | — | — | US | disclosed |
| JP-H02780-A | PURINYL AND PYRIDINYL CYCLO BUTANES | E R SQUIBB & SONS INC | 1990-01-05 | — | — | JP | disclosed |
| EP-0330992-A2 | Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them | Nippon Kayaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |
| US-4855466-A | Purinyl cyclobutanes | E. R. SQUIBB & SONS, INC. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0322854-A1 | Purinyl cyclobutanes | E.R. Squibb & Sons, Inc. (US) | 1989-07-05 | — | — | EP | disclosed |