SCHEMBL29323494

SCHEMBL29323494

C=C1NC(=O)C=CN1[C@@H]1O[C@H](CC)CC1N=[N+]=[N-]

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.33
▸ TSHR P16473 2/20 0.33
▸ TK1 P04183 2/20 0.33
▸ ALB P02768 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ PMP22 Q01453 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ ABCG2 Q9UNQ0 3/20 0.31
▸ ABCB1 P08183 1/20 0.31
▸ TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323126 1.00 LMNA (0.33) LMNATSHRTK1ALBPKM
SCHEMBL29323123 0.70 ALDH1A1 (0.42) LMNABLMPMP22
SCHEMBL29323492 0.70 ALDH1A1 (0.42) LMNABLMPMP22
SCHEMBL29323369 0.69 P2RY6 (0.44) LMNATSHRTK1ALBPKM
SCHEMBL17861787 0.65 — —
SCHEMBL25712268 0.64 ALDH1A1 (0.31) LMNAALB
SCHEMBL18016500 0.64 — —
SCHEMBL26311348 0.64 — —
SCHEMBL20250969 0.63 P2RY2 (0.30) —
SCHEMBL19600538 0.63 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY 2024-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES MTAP, PNP, SARS1 LMNA 424/4885TSHR 4089/4885TK1 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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