SCHEMBL29323652

SCHEMBL29323652

CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2ccc3c(ccc4onc(C5CCC(=O)NC5=O)c43)c2)CC1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 12/20 0.52
CRBN Q96SW2 12/20 0.52
CETP P11597 2/20 0.41
EPHX2 P34913 2/20 0.36
NOD2 Q9HC29 1/20 0.36
NOD1 Q9Y239 1/20 0.36
ALDH1A1 P00352 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323374 0.87 DDB1 (0.47) DDB1CRBNCETPEPHX2NOD2
SCHEMBL29323894 0.87 DDB1 (0.48) DDB1CRBNEPHX2ALDH1A1KDM4E
SCHEMBL29323657 0.86 CRBN (0.40) DDB1CRBNALDH1A1NPC1KDM4E
SCHEMBL23640001 0.86 DDB1 (0.49) DDB1CRBNEPHX2
SCHEMBL29322766 0.81 DDB1 (0.48) DDB1CRBNCETPEPHX2ALDH1A1
SCHEMBL29322819 0.81 DDB1 (0.50) DDB1CRBNCETPEPHX2ALDH1A1
SCHEMBL24302306 0.81 DDB1 (0.51) DDB1CRBN
SCHEMBL24302304 0.81 DDB1 (0.51) DDB1CRBN
SCHEMBL24303089 0.81 DDB1 (0.51) DDB1CRBN
SCHEMBL23640202 0.79 CRBN (0.44) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed