SCHEMBL29323894

SCHEMBL29323894

CC(C)(C)OC(=O)N1CCN(CC(=O)Nc2cccc3c2ccc2onc(C4CCC(=O)NC4=O)c23)CC1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 13/20 0.48
CRBN Q96SW2 13/20 0.48
PARP1 P09874 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP2C19 P33261 1/20 0.35
EPHX2 P34913 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323900 0.88 CYP2C19 (0.47) DDB1CRBNCHRM1KDM4EALDH1A1
SCHEMBL29321735 0.88 DDB1 (0.48) DDB1CRBNPARP1CHRM2CHRM4
SCHEMBL29323652 0.87 DDB1 (0.52) DDB1CRBNKDM4EALDH1A1EPHX2
SCHEMBL29323524 0.86 DDB1 (0.46) DDB1CRBNPARP1CHRM2CHRM4
SCHEMBL24754291 0.84 DDB1 (0.42) DDB1CRBN
SCHEMBL31444707 0.82 DDB1 (0.57) DDB1CRBNPARP1CHRM2CHRM4
SCHEMBL29323213 0.80 DDB1 (0.49) DDB1CRBNPARP1CHRM2CHRM4
SCHEMBL23640001 0.79 DDB1 (0.49) DDB1CRBNEPHX2
SCHEMBL29323602 0.78 DDB1 (0.46) DDB1CRBN
SCHEMBL24754173 0.76 DDB1 (0.36) DDB1CRBNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed