Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29323652 | 0.86 | DDB1 (0.52) | CRBNDDB1ALDH1A1KDM4ENPC1 | |
| SCHEMBL23639958 | 0.83 | CRBN (0.44) | CRBNDDB1GSPT1HTR1A | |
| SCHEMBL23640202 | 0.83 | CRBN (0.44) | CRBNDDB1GSPT1HTR1A | |
| SCHEMBL23640490 | 0.83 | CRBN (0.44) | CRBNDDB1GSPT1HTR1A | |
| SCHEMBL24754154 | 0.83 | ALDH1A1 (0.42) | CRBNDDB1ALDH1A1KDM4ENPC1 | |
| SCHEMBL24753996 | 0.81 | KDM4E (0.35) | CRBNDDB1ALDH1A1KDM4EMEN1 | |
| SCHEMBL24303037 | 0.81 | DRD2 (0.40) | CRBNDDB1PARP1HTR1A | |
| SCHEMBL24303028 | 0.81 | DRD2 (0.40) | CRBNDDB1PARP1HTR1A | |
| SCHEMBL23640005 | 0.81 | DRD2 (0.40) | CRBNDDB1PARP1HTR1A | |
| SCHEMBL24303027 | 0.79 | DDB1 (0.42) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |