SCHEMBL29323877

SCHEMBL29323877

C=C(C)C(=O)Oc1ccc(C(CS(=O)(=O)C2CCCCC2)CS(=O)(=O)C2CCCCC2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
ATM Q13315 1/20 0.40
ELANE P08246 1/20 0.39
BCHE P06276 1/20 0.35
MEN1 O00255 1/20 0.32
MITF O75030 1/20 0.32
FFAR1 O14842 2/20 0.32
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32
ENPP2 Q13822 1/20 0.32
LMNA P02545 1/20 0.32
MMP1 P03956 3/20 0.31
MMP13 P45452 3/20 0.31
MMP2 P08253 2/20 0.31
MMP3 P08254 2/20 0.31
MMP7 P09237 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ADAM17 P78536 2/20 0.31
MMP9 P14780 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323861 0.74 ELANE (0.51) KMT2AATMELANEMMP1MMP13
SCHEMBL29323860 0.73 ELANE (0.41) KMT2AATMELANEMEN1
SCHEMBL29323870 0.72 ELANE (0.49) KMT2AATMELANEMMP2MMP9
SCHEMBL1089780 0.71 KMT2A (0.49) KMT2AATMELANEMEN1SMN1; SMN2
SCHEMBL19789519 0.70 PARP10 (0.57) KMT2AATMELANEFFAR1MMP3
SCHEMBL18061417 0.70 ELANE (0.57) KMT2AATMELANEMEN1LMNA
SCHEMBL25926109 0.70 ELANE (0.57) KMT2AATMELANEMEN1LMNA
SCHEMBL22074734 0.69 ELANE (0.50) KMT2AATMELANEFFAR1LMNA
SCHEMBL56436 0.69 ELANE (0.69) KMT2AATMELANEMEN1LMNA
SCHEMBL13888358 0.69 ELANE (0.53) KMT2AATMELANELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed
US-20240241440-A1 POLYMER, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-07-18 US disclosed