Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.57 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.57 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907470 | 0.85 | PARP15 (0.47) | PARP10PARP15PARP2FFAR1KMT2A | |
| SCHEMBL9998782 | 0.81 | KMT2A (0.44) | PARP10PARP15KMT2AATMELANE | |
| SCHEMBL6958286 | 0.79 | PARP10 (0.72) | PARP10PARP15PARP2FFAR1KMT2A | |
| SCHEMBL24709164 | 0.78 | ALDH1A1 (0.55) | KMT2AATMELANEHPGD | |
| SCHEMBL1089780 | 0.78 | KMT2A (0.49) | KMT2AATMELANE | |
| SCHEMBL4117982 | 0.77 | PARP10 (0.71) | PARP10PARP15PARP2FFAR1KMT2A | |
| SCHEMBL9998674 | 0.76 | KMT2A (0.45) | PARP10PARP15PARP2KMT2AATM | |
| SCHEMBL56436 | 0.76 | ELANE (0.69) | KMT2AATMELANEHPGD | |
| SCHEMBL4403982 | 0.75 | ALDH1A1 (0.51) | KMT2AATMELANEHPGD | |
| SCHEMBL7603742 | 0.75 | ALDH1A1 (0.51) | KMT2AATMELANEHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |