SCHEMBL29323979

SCHEMBL29323979

COc1ccc(C(c2ccccc2)(c2ccc(OC)cc2)P(=O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
PKM P14618 1/20 0.45
HTT P42858 1/20 0.45
KIF11 P52732 5/20 0.44
KCNH2 Q12809 1/20 0.44
PTGS2 P35354 1/20 0.44
ACP3 P15309 1/20 0.44
MAPT P10636 1/20 0.43
CA4 P22748 1/20 0.43
HPGD P15428 1/20 0.42
LTA4H P09960 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323967 1.00 NPC1 (0.46) NPC1RAB9APKMHTTKIF11
SCHEMBL29323957 0.83 CA2 (0.44) PKMHTTMAPTCA4ALDH1A1
SCHEMBL13337695 0.81 HPGD (0.47) NPC1RAB9APKMHTTKIF11
SCHEMBL2362526 0.81 ACP3 (0.53) NPC1RAB9AKIF11KCNH2PTGS2
SCHEMBL2341405 0.81 ACP3 (0.53) NPC1RAB9AKIF11KCNH2PTGS2
SCHEMBL8717832 0.76 KIF11 (0.44) NPC1RAB9AKIF11KCNH2ACP3
SCHEMBL29323995 0.74 MAPT (0.60) RAB9APKMMAPTKDM4EALDH1A1
SCHEMBL22232956 0.74 KIF11 (0.45) NPC1RAB9APKMHTTKIF11
SCHEMBL7162911 0.74 ESR1 (0.57) NPC1RAB9APKMHTTPTGS2
SCHEMBL5619254 0.74 CA4 (0.54) NPC1RAB9APKMHTTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239974-A1 RESIN COMPOSITION, PREPREG USING SAME, FILM PROVIDED WITH RESIN, METAL FOIL PROVIDED WITH RESIN, METAL-CLAD LAMINATE, AND WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-07-18 US disclosed
US-20240239974-A1 RESIN COMPOSITION, PREPREG USING SAME, FILM PROVIDED WITH RESIN, METAL FOIL PROVIDED WITH RESIN, METAL-CLAD LAMINATE, AND WIRING BOARD PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2024-07-18 US disclosed