Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | CCNC | P24863 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056909 | 1.00 | KDM4E (0.35) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL29323704 | 0.83 | KDM4E (0.36) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL31056919 | 0.78 | KDM4E (0.40) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL29321031 | 0.78 | KDM4E (0.40) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL29323699 | 0.75 | KDM4E (0.38) | KDM4EGLAGAA | |
| SCHEMBL11296276 | 0.72 | KDM4E (0.51) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL29279278 | 0.71 | KMT2A (0.55) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL30336285 | 0.71 | KMT2A (0.55) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL16277802 | 0.70 | CYP46A1 (0.66) | KDM4EHTTHSD17B10ALDH1A1GLA | |
| SCHEMBL22460281 | 0.70 | KDM4E (0.43) | KDM4EHTTHSD17B10ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |