Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156267 | 0.90 | KDM4E (0.37) | KDM4EGLAGAAALOX5DRD2 | |
| SCHEMBL29323701 | 0.76 | KDM4E (0.36) | KDM4EGLAGAAALOX5NR4A2 | |
| SCHEMBL984048 | 0.76 | ALOX5 (0.57) | KDM4EGLAGAAALOX5TSHR | |
| SCHEMBL31056909 | 0.75 | KDM4E (0.35) | KDM4EGLAGAA | |
| SCHEMBL31056959 | 0.75 | SLC6A2 (0.34) | KDM4EGLAGAAALOX5DRD2 | |
| SCHEMBL29324065 | 0.75 | KDM4E (0.35) | KDM4EGLAGAA | |
| SCHEMBL29324068 | 0.75 | SLC6A2 (0.34) | KDM4EGLAGAAALOX5DRD2 | |
| SCHEMBL24776227 | 0.75 | NR3C2 (0.48) | KDM4EGLAGAAALOX5TSHR | |
| SCHEMBL24775927 | 0.74 | GRM5 (0.40) | KDM4EGLAGAAALOX5GRM5 | |
| SCHEMBL24776228 | 0.74 | GRM5 (0.46) | KDM4EGLAGAAALOX5GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |