Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLR1A | O95602 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324231 | 0.89 | HPGD (0.47) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29324219 | 0.86 | MAPT (0.41) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31103624 | 0.81 | PDE4A (0.47) | ALDH1A1HPGDSMN1; SMN2PDE4APDE4B | |
| SCHEMBL29324066 | 0.81 | PDE4A (0.47) | ALDH1A1HPGDSMN1; SMN2PDE4APDE4B | |
| SCHEMBL29324061 | 0.80 | PDE4A (0.44) | ALDH1A1HPGDSMN1; SMN2PDE4APDE4B | |
| SCHEMBL31103663 | 0.80 | PDE4A (0.44) | ALDH1A1HPGDSMN1; SMN2PDE4APDE4B | |
| SCHEMBL31103622 | 0.74 | ALDH1A1 (0.40) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16554644 | 0.73 | HPGD (0.47) | ALDH1A1HPGDMAPTKDM4EKMT2A | |
| SCHEMBL31103594 | 0.71 | ALDH1A1 (0.36) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10852270 | 0.68 | PDE4A (0.64) | ALDH1A1HPGDSMN1; SMN2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648770-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |