Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22134543 | 0.85 | NAAA (0.52) | TSHRRECQLCASP2MEN1KMT2A | |
| SCHEMBL860790 | 0.85 | KDM4E (0.56) | TSHRRECQLCASP2MEN1KMT2A | |
| SCHEMBL13129293 | 0.83 | CASP2 (0.69) | CASP2NAAAEPHX2POLBL3MBTL1 | |
| SCHEMBL4093621 | 0.83 | CASP2 (0.69) | CASP2NAAAEPHX2POLBL3MBTL1 | |
| SCHEMBL10728553 | 0.82 | CASP2 (0.57) | TSHRRECQLCASP2NAAAEPHX2 | |
| SCHEMBL15399777 | 0.82 | TSHR (0.65) | TSHRRECQLCASP2MEN1KMT2A | |
| SCHEMBL2771342 | 0.82 | RECQL (0.63) | TSHRRECQLCASP2MEN1KMT2A | |
| SCHEMBL21782549 | 0.81 | RECQL (0.48) | TSHRRECQLCASP2MEN1KMT2A | |
| SCHEMBL694512 | 0.81 | TSHR (0.64) | TSHRRECQLMEN1KMT2AEPHX2 | |
| SCHEMBL13376980 | 0.80 | RECQL (0.61) | TSHRRECQLCASP2NAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149992-A1 | IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS | UNIVERSITY OF DUNDEE (GB) | 2024-07-18 | — | — | WO | disclosed |