Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 7/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998017 | 1.00 | TGFBR1 (0.42) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL23807777 | 0.97 | SMPD3 (0.44) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL21997994 | 0.96 | TGFBR1 (0.44) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL23807919 | 0.96 | TGFBR1 (0.44) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL21998006 | 0.88 | ALDH1A1 (0.52) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL23744414 | 0.88 | ALDH1A1 (0.52) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL21998070 | 0.88 | ALDH1A1 (0.52) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL21997871 | 0.88 | ALDH1A1 (0.52) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL25968662 | 0.88 | ALDH1A1 (0.52) | TGFBR1SMPD3IRAK4KDM4EHSD17B10 | |
| SCHEMBL21998201 | 0.87 | IRAK4 (0.48) | TGFBR1SMPD3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894895-A | IRAK4 degradation agent and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023025159-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |
| CN-115710274-A | IRAK4 degradation agent, preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2023-02-24 | — | — | CN | disclosed |