Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319436 | 0.83 | GABRA1 (0.60) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL1242568 | 0.80 | GABRA1 (0.70) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL28289153 | 0.79 | GABRA1 (0.69) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7164261 | 0.78 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL28289180 | 0.77 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL13930267 | 0.77 | GABRA1 (0.67) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL5291640 | 0.76 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7290692 | 0.76 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL1075558 | 0.76 | ALDH1A1 (0.50) | GABRA1GABRB2MEN1KMT2ACYP1A2 | |
| SCHEMBL17242463 | 0.76 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151425-A1 | COMPOUNDS AND METHOD FOR TREATING HIV INFECTION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-18 | — | — | WO | disclosed |