Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 13/20 | 0.60 |
| ▸ | WNT1 | P04628 | 12/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | EP300 | Q09472 | 6/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK3 | P49761 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21285856 | 0.90 | WNT1 (0.73) | GSK3BDYRK1AWNT1MAPK8EP300 | |
| SCHEMBL29640907 | 0.90 | WNT1 (0.73) | GSK3BDYRK1AWNT1MAPK8EP300 | |
| SCHEMBL22953923 | 0.88 | EP300 (0.62) | GSK3BDYRK1AWNT1MAPK8EP300 | |
| SCHEMBL21285730 | 0.84 | EP300 (0.56) | GSK3BDYRK1AWNT1MAPK8EP300 | |
| SCHEMBL22953924 | 0.83 | MAPK8 (0.62) | GSK3BDYRK1AWNT1MAPK8EP300 | |
| SCHEMBL30238335 | 0.82 | MAP4K1 (0.55) | GSK3BDYRK1AWNT1EP300 | |
| SCHEMBL28508294 | 0.81 | CCNC (0.59) | GSK3BDYRK1AWNT1EP300 | |
| SCHEMBL29337529 | 0.80 | EP300 (0.59) | GSK3BDYRK1AWNT1MAPK8EP300 | |
| SCHEMBL30238347 | 0.80 | GSK3B (0.51) | GSK3BDYRK1AWNT1EP300CLK2 | |
| SCHEMBL21426361 | 0.80 | AURKB (0.74) | GSK3BDYRK1AWNT1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752497-B1 | P300/CBP HAT INHIBITORS | CONSTELLATION PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |