Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.59 |
| ▸ | CDK8 | P49336 | 2/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | WNT1 | P04628 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 10/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30238347 | 0.87 | GSK3B (0.51) | WNT1GSK3BDYRK1AABL1GPR55 | |
| SCHEMBL30238335 | 0.86 | MAP4K1 (0.55) | WNT1GSK3BDYRK1AABL1GPR55 | |
| SCHEMBL24932210 | 0.82 | GSK3B (0.56) | WNT1GSK3BDYRK1AABL1 | |
| SCHEMBL30006478 | 0.81 | GSK3B (0.78) | WNT1GSK3BDYRK1AABL1 | |
| SCHEMBL29324438 | 0.81 | GSK3B (0.60) | WNT1GSK3BDYRK1AEP300 | |
| SCHEMBL21255068 | 0.80 | GPR55 (0.57) | CREBBPWNT1GSK3BDYRK1AABL1 | |
| SCHEMBL30238470 | 0.79 | MAPK1 (0.47) | CCNCCDK8PIK3CGWNT1GSK3B | |
| SCHEMBL21285856 | 0.79 | WNT1 (0.73) | CREBBPWNT1GSK3BDYRK1AEP300 | |
| SCHEMBL29640907 | 0.79 | WNT1 (0.73) | CREBBPWNT1GSK3BDYRK1AEP300 | |
| SCHEMBL21426361 | 0.79 | AURKB (0.74) | CREBBPWNT1GSK3BDYRK1AEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218857-B | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114450005-A | Compounds for the treatment of neurological disorders | 星座制药公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-112218857-A | P300/CBP HAT inhibitors and methods of use thereof | 星座制药公司 | 2021-01-12 | — | — | CN | disclosed |