Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 15/20 | 0.61 |
| ▸ | DRD1 | P21728 | 9/20 | 0.61 |
| ▸ | DRD2 | P14416 | 7/20 | 0.61 |
| ▸ | HTR2A | P28223 | 5/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386472 | 0.91 | DRD3 (0.60) | DRD3DRD1DRD2DRD4 | |
| SCHEMBL9377321 | 0.86 | DRD3 (0.65) | DRD3DRD1DRD2HTR2ADRD4 | |
| SCHEMBL9376682 | 0.82 | DRD2 (0.60) | DRD3DRD2HTR7 | |
| SCHEMBL38653591 | 0.81 | DRD3 (0.55) | DRD3DRD1DRD2HTR2ADRD4 | |
| SCHEMBL9375915 | 0.81 | HTR7 (0.61) | DRD3DRD2HTR7 | |
| SCHEMBL9376168 | 0.81 | HTR7 (0.61) | DRD3DRD2HTR7 | |
| SCHEMBL19852195 | 0.78 | DRD3 (0.56) | DRD3DRD1DRD2HTR2ADRD4 | |
| SCHEMBL29322833 | 0.77 | DRD3 (0.51) | DRD3DRD1DRD2HTR2ADRD4 | |
| SCHEMBL1039709 | 0.77 | DRD3 (0.63) | DRD3DRD1DRD2DRD4 | |
| SCHEMBL9025470 | 0.77 | HRH1 (0.52) | DRD3DRD2DRD4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400504-A1 | THIOPHENE RING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CN) | 2024-07-17 | — | — | EP | disclosed |