Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.68 |
| ▸ | F11 | P03951 | 9/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23140022 | 0.85 | KLKB1 (0.69) | KLKB1F11F2CYP3A4CYP2C8 | |
| SCHEMBL17785396 | 0.84 | KLKB1 (0.84) | KLKB1F11F2 | |
| SCHEMBL17785353 | 0.81 | KLKB1 (0.80) | KLKB1F11F2 | |
| SCHEMBL21145581 | 0.81 | F11 (1.00) | KLKB1F11F2 | |
| SCHEMBL22993482 | 0.78 | KLKB1 (0.73) | KLKB1F11F2CYP3A4CYP2C8 | |
| SCHEMBL22993242 | 0.78 | KLKB1 (0.72) | KLKB1F11F2CYP3A4CYP2C8 | |
| SCHEMBL22993624 | 0.76 | KLKB1 (0.78) | KLKB1F11F2CYP3A4CYP2C8 | |
| SCHEMBL17785282 | 0.75 | F11 (1.00) | KLKB1F11F2 | |
| SCHEMBL19682326 | 0.74 | KLKB1 (0.68) | KLKB1F11F2CYP3A4CYP2C8 | |
| SCHEMBL17785343 | 0.73 | KLKB1 (0.74) | KLKB1F11F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031547-B1 | PLASMA KALLIKREIN INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-17 | — | — | EP | disclosed |