Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27226303 | 0.83 | KDR (0.53) | GPR119CHEK1RIPK1ALDH1A1KDR | |
| SCHEMBL19548104 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1TSHRRECQL | |
| SCHEMBL16894243 | 0.80 | P4HTM (0.45) | GPR119CHEK1P4HTMRIPK1CHEK2 | |
| SCHEMBL27226900 | 0.78 | GPR119 (0.54) | SMN1; SMN2NPC1GPR119CHEK1RIPK1 | |
| SCHEMBL21783486 | 0.77 | GPR119 (0.53) | GPR119ARCHEK1RIPK1KDR | |
| SCHEMBL16635426 | 0.77 | GPR119 (0.53) | GPR119ARCHEK1RIPK1KDR | |
| SCHEMBL25260940 | 0.76 | GPR119 (0.58) | GPR119CHEK1RIPK1CHEK2 | |
| SCHEMBL30339666 | 0.76 | GPR119 (0.58) | GPR119CHEK1RIPK1CHEK2 | |
| SCHEMBL3617657 | 0.76 | GPR119 (0.58) | GPR119ARCHEK1RIPK1ALDH1A1 | |
| SCHEMBL3486651 | 0.75 | GPR119 (0.57) | GPR119ARCHEK1RIPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239797-A1 | AKT1 MODULATORS | AKT1S1, AKT1, AKT2 | SMN1; SMN2 2237/4885RAB9A 1160/4885NPC1 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.