Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4281341 | 0.99 | IL1B (0.32) | IL1BGSK3BGPR6 | |
| SCHEMBL2932555 | 0.88 | — | — | |
| SCHEMBL4287394 | 0.85 | GSK3B (0.34) | IL1BGSK3BCNR1 | |
| SCHEMBL2934351 | 0.78 | CCR6 (0.41) | GSK3B | |
| Hydrochloric Acid SCHEMBL4281663 | 0.78 | CCR6 (0.41) | GSK3B | |
| SCHEMBL4284032 | 0.76 | GSK3B (0.49) | GSK3B | |
| SCHEMBL2935929 | 0.75 | GSK3B (0.33) | GSK3B | |
| SCHEMBL7956666 | 0.73 | GSK3B (0.47) | IL1BGSK3BGPR6CNR1 | |
| SCHEMBL3166285 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL2247528 | 0.73 | GSK3B (0.46) | IL1BGSK3BGPR6CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229392-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE AS GSK3BETA INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009074259-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | disclosed |