Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287394 | 0.85 | GSK3B (0.34) | GSK3B | |
| SCHEMBL2934351 | 0.80 | CCR6 (0.41) | GSK3B | |
| Hydrochloric Acid SCHEMBL4281663 | 0.80 | CCR6 (0.41) | GSK3B | |
| SCHEMBL2932471 | 0.76 | IL1B (0.33) | GSK3B | |
| Hydrochloric Acid SCHEMBL4281341 | 0.76 | IL1B (0.32) | GSK3B | |
| SCHEMBL4286336 | 0.73 | GSK3B (0.48) | GSK3B | |
| SCHEMBL12680894 | 0.70 | GSK3B (0.57) | GSK3B | |
| SCHEMBL12680787 | 0.69 | GSK3B (0.57) | GSK3B | |
| SCHEMBL4284030 | 0.68 | GSK3B (0.70) | GSK3B | |
| SCHEMBL8140792 | 0.66 | GSK3B (1.00) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258877-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE | BAYER HEALTHCARE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258877-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE | THPO, IL5, TPMT | GSK3B 2707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.