SCHEMBL29324914

SCHEMBL29324914

CC(=O)OC1[C@H](n2ccc(=O)[nH]c2=O)O[C@H](COC(=O)c2ccccc2)C1(C)OC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
KMT2A Q03164 1/20 0.42
NT5E P21589 1/20 0.41
P2RY2 P41231 5/20 0.37
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
P2RY12 Q9H244 4/20 0.37
HSD17B10 Q99714 1/20 0.36
P2RY6 Q15077 2/20 0.36
SLC28A1 O00337 1/20 0.36
SLC28A2 O43868 1/20 0.36
SLC29A1 Q99808 1/20 0.36
SLC28A3 Q9HAS3 1/20 0.36
P2RY14 Q15391 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29323315 0.85 SLC28A1 (0.41) NT5EP2RY2TDP1P2RY6SLC28A1
SCHEMBL29998581 0.80 P2RY6 (0.48) POLBMEN1USP2KMT2ANT5E
SCHEMBL29324916 0.80 NT5E (0.51) POLBMEN1USP2KMT2ANT5E
SCHEMBL30003828 0.80 GAPDH (0.38) POLBKMT2AALDH1A1
SCHEMBL27087661 0.79 ALDH1A1 (0.45) KMT2AALDH1A1
SCHEMBL20557502 0.79 ALDH1A1 (0.45) KMT2AALDH1A1
SCHEMBL16576324 0.79 ALDH1A1 (0.45) KMT2AALDH1A1
SCHEMBL29324933 0.79 ALDH1A1 (0.45) KMT2AALDH1A1
SCHEMBL7161171 0.78 NT5E (0.43) POLBMEN1USP2KMT2ANT5E
SCHEMBL29989951 0.78 MEN1 (0.63) POLBMEN1USP2KMT2AP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES EMORY UNIVERSITY 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238323-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES ANALOGS AS ANTIVIRAL AGENTS FOR CORONA AND OTHER VIRUSES MTAP, PNP, SARS1 POLB 238/4885MEN1 3639/4885USP2 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.