Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | MERTK | Q12866 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325879 | 1.00 | IRAK4 (0.35) | IRAK4MAPK8MKNK1MKNK2CCNT1 | |
| SCHEMBL29325964 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL29326234 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL29155922 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL29155917 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL29325972 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL29326237 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL30684778 | 0.91 | MAPK8 (0.39) | MAPK8CCNT1CDK9PTPN11MAPK9 | |
| SCHEMBL29325869 | 0.91 | MAPK10 (0.36) | IRAK4MAPK8MKNK2CDK9TYRO3 | |
| SCHEMBL31039775 | 0.81 | CCNK (0.34) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NICO THERAPEUTICS, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239758-A1 | SUBSTITUTED TRIAZINE COMPOUND | NLRP3, NLRP1, PYCARD | IRAK4 47/4885MAPK8 3960/4885MKNK1 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.