Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326105 | 0.86 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL29328234 | 0.84 | — | — | |
| SCHEMBL29326101 | 0.84 | HTR2A (0.30) | HTR2AHTR2CHTR2B | |
| SCHEMBL15339521 | 0.80 | MAOA (0.33) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL29328231 | 0.74 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL26835702 | 0.73 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL26355591 | 0.73 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL15339520 | 0.71 | ACHE (0.31) | — | |
| SCHEMBL8737441 | 0.70 | MAOA (0.37) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL8466373 | 0.70 | HTR2C (0.39) | HTR2AHTR2CHTR2BMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | HTR2A 2757/4885HTR2C 1491/4885HTR2B 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.