Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.39 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377878 | 0.89 | DHODH (0.41) | MCL1DHODHPTGER1PTGER4PTGER3 | |
| SCHEMBL29326298 | 0.87 | MCL1 (0.46) | MCL1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29326224 | 0.83 | NPEPPS (0.48) | MCL1NPEPPSPKMHSD17B10FEN1 | |
| SCHEMBL29326210 | 0.83 | ERCC5 (0.40) | DHODHPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29326302 | 0.80 | NPEPPS (0.43) | MCL1NPEPPSPKMHSD17B10FEN1 | |
| SCHEMBL29326223 | 0.80 | FEN1 (0.58) | NPEPPSPKMHSD17B10FEN1TNKS2 | |
| SCHEMBL29326363 | 0.79 | TNKS2 (0.50) | NPEPPSFEN1TNKS2 | |
| SCHEMBL29326236 | 0.79 | NPEPPS (0.44) | NPEPPSPKMHSD17B10FEN1TNKS2 | |
| SCHEMBL29326335 | 0.78 | NPEPPS (0.43) | MCL1NPEPPSPKMHSD17B10FEN1 | |
| SCHEMBL29326311 | 0.78 | KDM4E (0.47) | NPEPPSFEN1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | MCL1 4265/4885DHODH 1223/4885PTGER1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.