Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | WEE1 | P30291 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29326398 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL27378159 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326306 | 0.86 | GRIA1 (0.53) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326212 | 0.81 | HSD17B10 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326281 | 0.79 | GRIA1 (0.44) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL27378173 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326391 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326386 | 0.78 | KDM4E (0.40) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326420 | 0.77 | HSD17B10 (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2HIF1A | |
| SCHEMBL29326437 | 0.77 | KDM4E (0.50) | KDM4EHSD17B10PKMTP53NPEPPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | ALDH1A1 3259/4885KDM4E 3744/4885HPGD 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.