Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 5/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191849 | 0.91 | KDM4E (0.40) | KDM4ENPC1RAB9AALDH1A1GPR55 | |
| SCHEMBL30702116 | 0.91 | KDM4E (0.40) | KDM4ENPC1RAB9AALDH1A1GPR55 | |
| SCHEMBL29326451 | 0.86 | KDM4E (0.45) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326437 | 0.86 | KDM4E (0.50) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326751 | 0.84 | PTGES (0.41) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326363 | 0.83 | TNKS2 (0.50) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326576 | 0.82 | PTGES (0.40) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326448 | 0.82 | ITGA4 (0.42) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326611 | 0.81 | PTGES (0.48) | KDM4EHTTPTGESNPEPPSCYP2C9 | |
| SCHEMBL29326311 | 0.81 | KDM4E (0.47) | KDM4EHTTPTGESNPEPPSCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239807-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | ACE2, TMPRSS2, ACE | KDM4E 3744/4885NPC1 848/4885RAB9A 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.