Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 14/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 12/20 | 0.56 |
| ▸ | CDK9 | P50750 | 9/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 9/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 7/20 | 0.56 |
| ▸ | CSNK1A1 | P48729 | 7/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.53 |
| ▸ | CDK1 | P06493 | 4/20 | 0.53 |
| ▸ | CCNK | O75909 | 2/20 | 0.53 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.53 |
| ▸ | CDK7 | P50613 | 2/20 | 0.53 |
| ▸ | CCNH | P51946 | 2/20 | 0.53 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.53 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112174 | 0.91 | CDK2 (0.58) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19112166 | 0.86 | CDK2 (0.72) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19112176 | 0.85 | CDK2 (0.61) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19111955 | 0.85 | CDK2 (0.75) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19139043 | 0.85 | CDK2 (0.75) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19112097 | 0.85 | CDK2 (0.75) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL15372679 | 0.83 | CDK2 (0.78) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL23993156 | 0.83 | CDK2 (0.60) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19112345 | 0.81 | CDK2 (0.57) | CDK2CCNA2CCNA1CDK9CDK5 | |
| SCHEMBL19112010 | 0.78 | CDK2 (0.42) | CDK2CCNA2CCNA1CDK9CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139308-B1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2024-07-17 | — | — | EP | disclosed |