Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 4/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631227 | 0.90 | MPO (0.58) | MPOTAAR1LMNASLC6A4SCN8A | |
| SCHEMBL6071681 | 0.81 | MPO (0.60) | MPOTAAR1LMNASLC6A4SCN8A | |
| SCHEMBL21674321 | 0.78 | MPO (0.59) | MPOTAAR1LMNASLC6A4SCN8A | |
| SCHEMBL6819 | 0.77 | TAAR1 (0.63) | MPOTAAR1LMNASLC6A4L3MBTL1 | |
| SCHEMBL2101041 | 0.77 | GAA (0.42) | SLC6A4GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL13975772 | 0.76 | MPO (0.61) | MPOTAAR1SLC6A4SCN8AKMT2A | |
| SCHEMBL17033966 | 0.74 | TAAR1 (0.66) | MPOTAAR1KMT2AMEN1HPGD | |
| SCHEMBL18405175 | 0.74 | SCN8A (0.58) | MPOTAAR1LMNASLC6A4SCN8A | |
| SCHEMBL20905865 | 0.74 | MPO (0.58) | MPOTAAR1LMNASLC6A4SCN8A | |
| SCHEMBL23613102 | 0.73 | L3MBTL1 (0.57) | MPOTAAR1LMNASLC6A4SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400502-A2 | TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Shionogi & Co., Ltd (JP) | 2024-07-17 | — | — | EP | disclosed |