Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.46 |
| ▸ | MC3R | P41968 | 6/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | MC1R | Q01726 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028098 | 1.00 | MC4R (0.46) | MC4RMC3RMC5RKCNH2DPP4 | |
| SCHEMBL29327394 | 0.88 | DPP4 (0.51) | MC4RMC3RMC5RKCNH2DPP4 | |
| SCHEMBL4615034 | 0.88 | DPP4 (0.51) | MC4RMC3RMC5RKCNH2DPP4 | |
| SCHEMBL12536904 | 0.84 | PANK3 (0.45) | MC4RMC3RMC5RKCNH2MC1R | |
| SCHEMBL15039509 | 0.84 | PANK3 (0.45) | MC4RMC3RMC5RKCNH2MC1R | |
| SCHEMBL15039510 | 0.79 | MC4R (0.46) | MC4RMC3RMC5RKCNH2MC1R | |
| SCHEMBL2307981 | 0.79 | KMT2A (0.49) | MC4RMC3RMC5RKCNH2MC1R | |
| SCHEMBL4603259 | 0.78 | MC4R (0.54) | MC4RMC3RMC5RKCNH2MC1R | |
| SCHEMBL12536922 | 0.78 | MC4R (0.42) | MC4RMC3RMC5RKCNH2MC1R | |
| SCHEMBL4603038 | 0.78 | MC4R (0.51) | MC4RMC3RMC5RKCNH2MC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | AQP3, SLC6A7, ABCG2 | MC4R 2367/4885MC3R 1834/4885MC5R 1441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.