Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.39 |
| ▸ | HTR2C | P28335 | 13/20 | 0.39 |
| ▸ | HTR2B | P41595 | 13/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29327276 | 0.79 | HTR2C (0.41) | HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL29327284 | 0.77 | HTR2C (0.50) | HTR2AHTR2CHTR2BCHRNB2CHRNB4 | |
| SCHEMBL5632465 | 0.77 | RAD52 (0.49) | HTR2AHTR2CHTR2BADAMTS5 | |
| SCHEMBL5630960 | 0.77 | RAD52 (0.49) | HTR2AHTR2CHTR2BADAMTS5 | |
| SCHEMBL5630952 | 0.77 | RAD52 (0.49) | HTR2AHTR2CHTR2BADAMTS5 | |
| Hydrochloric Acid SCHEMBL5631799 | 0.76 | RAD52 (0.51) | HTR2AHTR2CHTR2BADAMTS5 | |
| Hydrochloric Acid SCHEMBL5631792 | 0.76 | RAD52 (0.51) | HTR2AHTR2CHTR2BADAMTS5 | |
| SCHEMBL29327433 | 0.76 | HTR2A (0.43) | HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL4939187 | 0.75 | SLC6A2 (0.49) | HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL4939192 | 0.75 | SLC6A2 (0.49) | HTR2AHTR2CHTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238281-A1 | PIPERAZINE DERIVATIVES AND APPLICATION THEREOF | AQP3, SLC6A7, ABCG2 | HTR2A 774/4885HTR2C 491/4885HTR2B 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.