Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620738 | 0.86 | MAOA (0.55) | PBRM1EGFRHSD17B1MAOAMAOB | |
| SCHEMBL423181 | 0.86 | MAOA (0.60) | PBRM1EGFRHSD17B1MAOAMAOB | |
| SCHEMBL10102257 | 0.83 | PBRM1 (0.50) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL1032102 | 0.83 | PBRM1 (0.50) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL29033 | 0.83 | HSD17B1 (0.60) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL25269929 | 0.83 | HSD17B1 (0.60) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL2930139 | 0.83 | PBRM1 (0.50) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL2304058 | 0.83 | PBRM1 (0.50) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL1562728 | 0.83 | PBRM1 (0.50) | PBRM1EGFRHSD17B1CASP1CASP7 | |
| SCHEMBL9520543 | 0.83 | PBRM1 (0.50) | PBRM1EGFRHSD17B1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186044-A | Benzofuranone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-105237383-A | Indanone derivative 5,6-dyhydroxy-2,3-dihydrocaroone-1H-indene-1-ketone and preparation method thereof | UNIV HEILONGJIANG | 2016-01-13 | — | — | CN | claimed |
| CN-117229244-A | Orange ketone analogue and application thereof | 中国科学院新疆理化技术研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-117186044-A | Benzofuranone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-12-08 | — | — | CN | disclosed |
| CN-105985265-B | Indenes -1- subunit sulfonyl benzoyl hydrazine derivatives and its preparation method and application | 四川大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-103998422-B | Cyclopentanedione oxime ester and application thereof | 北京英力科技发展有限公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-105985265-A | Indene-1-subunit sulfonyl benzoyl hydrazine derivative as well as preparation method and application thereof | 四川大学 | 2016-10-05 | — | — | CN | disclosed |
| CN-105237383-A | Indanone derivative 5,6-dyhydroxy-2,3-dihydrocaroone-1H-indene-1-ketone and preparation method thereof | UNIV HEILONGJIANG | 2016-01-13 | — | — | CN | disclosed |
| EP-1740579-B1 | TRICYCLIC PYRAZOLE KINASE INHIBITORS | ABBVIE INC (US) | 2015-08-19 | — | — | EP | disclosed |
| WO-2015027702-A1 | CYCLOPENTANEDIONE OXIME ESTER AND APPLICATION THEREOF | 北京英力科技发展有限公司 (CN) | 2015-03-05 | — | — | WO | disclosed |
| WO-2015027833-A1 | CYCLOPENTADIONE OXIME ESTER AND APPLICATION THEREOF | 北京英力科技发展有限公司 (CN) | 2015-03-05 | — | — | WO | disclosed |
| WO-1993011258-A1 | METHOD FOR ASSAYING THE SOD ACTIVITY BY USING A SELF-OXIDIZABLE COMPOUND NECESSARY FOR ITS IMPLEMENTATION, SELF-OXIDIZABLE COMPOUNDS AND PREPARATION THEREOF | BIOXYTECH (FR) | 1993-06-10 | — | — | WO | disclosed |
| US-5217999-A | Antigrowth agents | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1993-06-08 | — | — | US | disclosed |
| US-5198585-A | Catalytic hydrogenation of arylisonitrosoalkanone | HOECHST CELANESE CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |
| WO-1993001158-A1 | METHOD FOR THE PREPARATION OF ARYLKETOAMINES | HOECHST CELANESE CORPORATION (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5175368-A | Hydrogenating aryl alpha-oximinoalkyl ketones in aqueous medium containing hydrochlroic acid, recovering salt | HOECHST CELANESE CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0491557-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0481705-A1 | Process for the preparation of arylalkylamines and substituted arylalkylamines | HOECHST CELANESE CORPORATION (US) | 1992-04-22 | — | — | EP | disclosed |
| WO-1991016892-A1 | STYRYL COMPOUNDS WHICH INHIBIT EGF RECEPTOR PROTEIN TYROSINE KINASE | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-11-14 | — | — | WO | disclosed |
| US-5041669-A | Reacting alkyl aryl ketones with alkyl nitrites, extracting product, catalytically hydrogenating/reducing in nonaqueous acid mixture | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |