Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4287767 | 0.99 | SCN10A (0.32) | SCN10A | |
| SCHEMBL2935929 | 0.93 | GSK3B (0.33) | — | |
| SCHEMBL2936764 | 0.92 | — | — | |
| SCHEMBL2974024 | 0.82 | GSK3B (0.33) | SCN10A | |
| SCHEMBL2926625 | 0.75 | CNR1 (0.33) | — | |
| SCHEMBL2932471 | 0.69 | IL1B (0.33) | — | |
| Hydrochloric Acid SCHEMBL4281341 | 0.68 | IL1B (0.32) | — | |
| SCHEMBL2932555 | 0.68 | — | — | |
| SCHEMBL8039872 | 0.68 | GSK3B (0.39) | SCN10A | |
| Hydrochloric Acid SCHEMBL4287764 | 0.67 | GSK3B (0.38) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229392-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THEIR USE AS GSK3BETA INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009074259-A1 | TRIAZOLOTRIAZINES AND TRIAZOLOPYRAZINES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-18 | — | — | WO | disclosed |