Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1924139 | 0.84 | ALDH1A1 (0.57) | MAPTNPC1ALDH1A1CA1CA2 | |
| SCHEMBL11391147 | 0.82 | CA1 (0.64) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13731179 | 0.82 | ALDH1A1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13916848 | 0.81 | NPC1 (0.58) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL12142808 | 0.80 | ESR1 (0.39) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14504336 | 0.79 | PTPN1 (0.50) | MAPTRAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL6168439 | 0.79 | PLOD2 (0.56) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL26134425 | 0.78 | MEN1 (0.65) | MAPTRAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL6339289 | 0.78 | ERCC5 (0.56) | MAPTRAB9ANPC1ALDH1A1POLB | |
| SCHEMBL29083842 | 0.78 | GSK3B (0.53) | RAB9ANPC1HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |