SCHEMBL29328698

SCHEMBL29328698

CCOC(=O)C1CCC2(CCC(C)(C)CC(C)(C)C2)C1=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 3/20 0.38
HSD17B10 Q99714 3/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 2/20 0.38
TLR4 O00206 1/20 0.35
PTPN2 P17706 1/20 0.32
PTPN1 P18031 1/20 0.32
CDC25B P30305 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29328751 0.78 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL15416050 0.78 TLR4 (0.45) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL29329219 0.78 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL15831723 0.77 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL16540969 0.75 TLR4 (0.45) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL25248672 0.73 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL855129 0.72 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL6901618 0.68 TLR4 (0.44) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL8943213 0.68 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL6559393 0.68 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151112-A1 PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR 주식회사 티움바이오 2024-07-18 WO disclosed