Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938633 | 0.89 | SIRT2 (0.35) | METTRPA1GALR2CHEK1 | |
| SCHEMBL29330952 | 0.89 | SIRT2 (0.35) | METTRPA1GALR2CHEK1 | |
| SCHEMBL30938642 | 0.89 | SIRT2 (0.35) | METTRPA1GALR2CHEK1 | |
| SCHEMBL29330500 | 0.88 | P2RY14 (0.35) | CDK2TRPA1GALR2CDK4KDM4E | |
| SCHEMBL29333406 | 0.85 | SIRT2 (0.35) | METGALR2KDM4EGAAHPGD | |
| SCHEMBL29330495 | 0.83 | IMPDH2 (0.38) | MET | |
| SCHEMBL29330502 | 0.82 | KCNH2 (0.39) | METTRPA1GALR2 | |
| SCHEMBL29329939 | 0.82 | APP (0.38) | NTRK3METTRPA1 | |
| SCHEMBL29328813 | 0.82 | CDK4 (0.33) | CDK2METTRPA1GALR2CDK4 | |
| SCHEMBL29331093 | 0.81 | KDM4E (0.35) | METMAPTKDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |