Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938633 | 1.00 | SIRT2 (0.35) | SIRT2METPPARAPPARDP2RY14 | |
| SCHEMBL30938642 | 1.00 | SIRT2 (0.35) | SIRT2METPPARAPPARDP2RY14 | |
| SCHEMBL29330500 | 0.92 | P2RY14 (0.35) | P2RY14CHRNA7APPTRPA1GALR2 | |
| SCHEMBL29330495 | 0.91 | IMPDH2 (0.38) | METPPARAP2RY14EGFRKDR | |
| SCHEMBL29333406 | 0.91 | SIRT2 (0.35) | SIRT2METPPARAPPARDP2RY14 | |
| SCHEMBL29329939 | 0.89 | APP (0.38) | METCHRNA7APPKDRTRPA1 | |
| SCHEMBL29328811 | 0.89 | CDK2 (0.32) | METCHEK1TRPA1GALR2 | |
| SCHEMBL29331084 | 0.87 | SIRT2 (0.35) | SIRT2METPPARAPPARDCHEK1 | |
| SCHEMBL29330715 | 0.87 | CHRNA7 (0.35) | SIRT2METPPARAPPARDCHRNA7 | |
| SCHEMBL29330502 | 0.87 | KCNH2 (0.39) | METAPPKDRTRPA1GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |