Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.77 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.77 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.77 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.77 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.77 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.77 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.77 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.52 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176692 | 1.00 | LPAR1 (0.77) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL27784094 | 0.89 | LPAR1 (0.97) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL2932933 | 0.89 | LPAR1 (0.97) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL8508530 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL8509455 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL2935665 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL2935599 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL8509038 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL8736955 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 | |
| SCHEMBL13043253 | 0.87 | LPAR1 (1.00) | LPAR1ENPP2LPAR3LPAR4LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |