Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329256 | 0.89 | MAPT (0.44) | ALDH1A1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29329240 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28346466 | 0.84 | KMT2A (0.47) | ALDH1A1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL19463055 | 0.83 | HDAC8 (0.47) | ALDH1A1MAPTL3MBTL1KMT2ALMNA | |
| Lithium Ion SCHEMBL19464083 | 0.82 | KMT2A (0.44) | ALDH1A1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29329260 | 0.80 | TSHR (0.47) | ALDH1A1RAB9AKMT2APLAUELANE | |
| SCHEMBL2367563 | 0.78 | BACE1 (0.42) | ALDH1A1MAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL19689391 | 0.78 | KIF11 (0.38) | SMN1; SMN2PLAUELANELMNAHTT | |
| SCHEMBL19463046 | 0.78 | KIF11 (0.43) | RAB9ANPC1 | |
| SCHEMBL16618219 | 0.78 | CYP1A2 (0.38) | SMN1; SMN2KMT2APLAUELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |