Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 7/20 | 0.39 |
| ▸ | KDR | P35968 | 7/20 | 0.38 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329748 | 0.87 | KDR (0.41) | TRPC5KDRTRPC4KCNH2TRPA1 | |
| SCHEMBL29329343 | 0.82 | TRPC5 (0.41) | TRPC5KDRTRPC4KCNH2TRPA1 | |
| SCHEMBL30603341 | 0.80 | TRPC5 (0.55) | TRPC5KDRTRPC4KCNH2TRPA1 | |
| SCHEMBL21807225 | 0.80 | TRPC5 (0.55) | TRPC5KDRTRPC4KCNH2TRPA1 | |
| SCHEMBL29090290 | 0.80 | TRPC5 (0.55) | TRPC5KDRTRPC4KCNH2TRPA1 | |
| SCHEMBL29090296 | 0.80 | KDR (0.41) | TRPC5KDRTRPC4KCNH2TRPA1 | |
| SCHEMBL30603350 | 0.79 | TRPC5 (0.55) | TRPC5KDRTRPC4 | |
| SCHEMBL29090308 | 0.79 | TRPC5 (0.55) | TRPC5KDRTRPC4 | |
| SCHEMBL29090295 | 0.77 | HSPB1 (0.40) | TRPC5KDRTRPC4KCNH2 | |
| SCHEMBL21807310 | 0.72 | KDR (0.38) | TRPC5KDRKCNH2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400500-A1 | HALOGEN-SUBSTITUTED PYRIDAZINONE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |