Ciaftalan

Ciaftalan

SCHEMBL293303

O[GaH2].[MgH2].c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21.c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
RECQL P46063 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
THRB P10828 1/20 0.45
APEX1 P27695 1/20 0.45
BLM P54132 1/20 0.45
CA5A P35218 1/20 0.37
POLB P06746 3/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 2/20 0.33
MAPK1 P28482 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ciaftalan SCHEMBL3166730 0.98 MEN1 (0.44) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL74723 0.98 MEN1 (0.46) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL5094879 0.98 MEN1 (0.46) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL4543771 0.96 MEN1 (0.45) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL38541 0.94 MEN1 (0.45) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL4444596 0.92 MEN1 (0.44) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL8909497 0.92 MEN1 (0.44) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL27326363 0.92 MEN1 (0.44) MEN1KMT2ARECQLTDP1THRB
SCHEMBL813083 0.92 MEN1 (0.46) MEN1KMT2ARECQLTDP1THRB
Ciaftalan SCHEMBL1728179 0.92 MEN1 (0.46) MEN1KMT2ARECQLTDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7794905-B2 Photoreceptor device having a self-assembled patterned binder layer XEROX CORPORATION (US) 2010-09-14 US claimed
US-20100068636-A1 PHOTORECEPTOR PROTECTIVE OVERCOAT LAYER INCLUDING SILICONE POLYETHER AND METHOD OF MAKING SAME XEROX CORPORATION (US) 2010-03-18 US claimed
US-20080233500-A1 PHOTORECEPTOR DEVICE HAVING A SELF-ASSEMBLED PATTERNED BINDER LAYER XEROX CORPORATION (US) 2008-09-25 US claimed
EP-2098912-B1 SELF-HEALING PHOTOCONDUCTIVE MEMBER XEROX CORP (US) 2017-08-30 EP disclosed
EP-2112557-B1 Imaging member and imaging apparatus using the same XEROX CORP (US) 2015-11-04 EP disclosed
US-8883384-B2 Binderless overcoat layer XEROX CORPORATION (US) 2014-11-11 US disclosed
EP-2098913-B1 Photoconductive member XEROX CORP (US) 2014-06-25 EP disclosed
EP-1973001-B1 Photoreceptor device having a self-assembled patterned binder layer XEROX CORP (US) 2013-08-28 EP disclosed
EP-1632814-B1 Inorganic material surface grafted with charge transport moiety XEROX CORP (US) 2013-06-26 EP disclosed
US-8309285-B2 Protective overcoat layer and photoreceptor including same XEROX CORPORATION (US) 2012-11-13 US disclosed
EP-1892577-B1 Photoreceptor XEROX CORP (US) 2012-10-10 EP disclosed
US-6207334-B1 ELECTROGRAPHY IMAGES, CHARGE GENERTING LAYER, CHARGE TRANSPORT LAYER, OVERCOATING LAYER AND POLYVINYL BUTYRAL, CROSSLINKED POLYIMIDE WITH HOLE TRANSPORT XEROX CORPORATION 2001-03-27 US disclosed
US-6197464-B1 WEAR RESISTANCE; ADHESION XEROX CORPORATION 2001-03-06 US disclosed
EP-1014205-A2 Electrophotographic imaging member comprising an overcoat layer and process of preparation Xerox Corporation (US) 2000-06-28 EP disclosed
EP-1013695-A1 Allyloxymethylated polyamide synthesis, compositions and devices Xerox Corporation (US) 2000-06-28 EP disclosed
US-6071659-A Stabilized overcoat compositions XEROX CORPORATION (US) 2000-06-06 US disclosed
US-6004709-A Allyloxymethylatedpolyamide synthesis compositions and devices XEROX CORPORATION (US) 1999-12-21 US disclosed
EP-0660191-B1 Layered photoreceptor with overcoatings containing hydrogen bonded materials XEROX CORP (US) 1998-10-21 EP disclosed
EP-0660191-A1 Layered photoreceptor with overcoatings containing hydrogen bonded materials XEROX CORPORATION (US) 1995-06-28 EP disclosed
US-5368967-A Layered photoreceptor with overcoat containing hydrogen bonded materials XEROX CORPORATION (US) 1994-11-29 US disclosed