SCHEMBL29330319

SCHEMBL29330319

NS(=O)(=O)[C@H]1CC[C@@H](N)CC1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.39
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14639228 1.00 APLNR (0.39) APLNRCA1CA2
SCHEMBL8263 0.87
SCHEMBL8099149 0.87 APLNR (0.46) APLNRCA1CA2
SCHEMBL9122745 0.84
Bromide SCHEMBL30609926 0.84
Hydrochloric Acid SCHEMBL19987689 0.84
SCHEMBL23548930 0.83 APLNR (0.37) APLNRCA1CA2
SCHEMBL933808 0.79 SMYD3 (0.31)
SCHEMBL5596636 0.79 SMYD3 (0.31)
Oxirane SCHEMBL25299382 0.77 APLNR (0.39) APLNRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151112-A1 PYRAZOLOPYRIMIDINE DERIVATIVE AS CYCLIN-DEPENDENT KINASE 9 INHIBITOR 주식회사 티움바이오 2024-07-18 WO disclosed