⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099149 | 1.00 | APLNR (0.46) | — | |
| SCHEMBL9122745 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL19987689 | 0.96 | — | — | |
| Bromide SCHEMBL30609926 | 0.96 | — | — | |
| Oxirane SCHEMBL25299382 | 0.87 | APLNR (0.39) | — | |
| SCHEMBL29330319 | 0.87 | APLNR (0.39) | — | |
| SCHEMBL14639228 | 0.87 | APLNR (0.39) | — | |
| Propane SCHEMBL28815736 | 0.87 | APLNR (0.39) | — | |
| SCHEMBL5514036 | 0.87 | APLNR (0.39) | — | |
| SCHEMBL244348 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6380 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3826722-B1 | ISOQUINOLINE COMPOUNDS AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2026-02-18 | — | — | EP | claimed |
| EP-3623372-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH INC (US) | 2026-02-04 | — | — | EP | claimed |
| EP-3717459-B1 | COMPOUNDS | STEP PHARMA S A S (FR) | 2026-01-21 | — | — | EP | claimed |
| EP-4143185-B1 | NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | PERHA PHARMACEUTICALS (FR) | 2025-10-29 | — | — | EP | claimed |
| US-12448377-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-10-21 | — | — | US | claimed |
| EP-3525785-B1 | KDM5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-08-27 | — | — | EP | claimed |
| CN-120040345-A | KIF18A inhibitory activity small molecule compound, and pharmaceutical composition and application thereof | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2025-05-27 | — | — | CN | claimed |
| WO-2025104411-A1 | THERAPEUTIC COMPOUNDS | C4X DISCOVERY LIMITED (GB) | 2025-05-22 | — | — | WO | claimed |
| WO-2025080592-A1 | COMBINATION COMPRISING A KRAS G12D INHIBITOR AND AN EGFR INHIBITOR FOR USE IN THE TREATMENT OF CANCER | INCYTE CORPORATION (US) | 2025-04-17 | — | — | WO | claimed |
| WO-2025080593-A1 | COMBINATION THERAPY USING A KRAS G12D INHIBITOR AND PD-1 INHIBITOR OR PD-L1 INHIBITOR | INCYTE CORPORATION (US) | 2025-04-17 | — | — | WO | claimed |
| US-20050054534-A1 | Substituted benzoylcyclohexane diones for use as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-03-10 | — | — | US | claimed |
| EP-0906291-B1 | SUBSTITUTED PHENYL URACILS | BAYER CROPSCIENCE AG (DE) | 2005-03-09 | — | — | EP | claimed |
| US-6825183-B2 | CONTROLLING PLANTS; ANTIGROWTH AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | claimed |
| EP-1244634-B1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-03-17 | — | — | EP | claimed |
| US-20030119674-A1 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-26 | — | — | US | claimed |
| EP-1244634-A1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER AG (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047894-A1 | SUBSTITUTED BENZOYLCYCLOHEXANE DIONES FOR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-1999052906-A1 | SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | claimed |
| EP-0906291-A1 | SUBSTITUTED PHENYL URACILS | BAYER AG (DE) | 1999-04-07 | — | — | EP | claimed |
| WO-1997045418-A1 | SUBSTITUTED PHENYL URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | claimed |