Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29329722 | 0.88 | SYK (0.41) | PRKCQSYKMETESR1RET | |
| SCHEMBL29330425 | 0.86 | ESR1 (0.42) | PRKCQSYKMETESR1RET | |
| SCHEMBL29329536 | 0.85 | SYK (0.40) | PRKCQSYKMETESR1RET | |
| SCHEMBL29330567 | 0.85 | PRKCQ (0.45) | PRKCQSYKESR1RETMEN1 | |
| SCHEMBL29330256 | 0.84 | PRKCQ (0.41) | PRKCQNOTUMSYKMETESR1 | |
| SCHEMBL29329126 | 0.84 | SYK (0.40) | PRKCQNOTUMSYKMETESR1 | |
| SCHEMBL29328747 | 0.84 | EGFR (0.42) | PRKCQSYKMETESR1SLC2A1 | |
| SCHEMBL29329781 | 0.84 | SYK (0.41) | PRKCQSYKMETESR1RET | |
| SCHEMBL29330161 | 0.83 | ESR1 (0.48) | PRKCQSYKESR1MEN1POLB | |
| SCHEMBL29329863 | 0.83 | SYK (0.40) | PRKCQSYKMETESR1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |